TNFSF10 and neoplasm: In this context, a decrease in the processing of non-proapoptotic TRAIL variants (i.e. TRAIL-β and TRAIL-γ) as we observed in gastric carcinomas could permit the increase of translated TRAIL-α which in turn could induce programmed cell death in tumour infiltrating immune cells and thus promoting the immune escape and tumour surveillance of gastric carcinomas.