When added to the multivariate model to study the association of the markers with PWV independently of eGFR, age, systolic blood pressure, sex, presence or absence of CAD and body mass index only E-selectin (β = 0.307, P < 0.001; also included: age [β = 0.617, P < 0.001]), osteopontin (β = 0.336, P < 0.001; also included: age [β = 0.538, P < 0.001], body mass index [β = 0.188, P = 0.021]) and adiponectin (β = 0.203, P = 0.017; also included: age [β = 0.502, P < 0.001], eGFR [β = − 0.186, P = 0.036] and systolic blood pressure [β = 0.215, P = 0.014]) were part of the final models. The gene discussed is SPP1; the disease is coronary artery disorder.