However, the sample of LN in our study was homogeneous in ethnicity, proven by biopsy, and all enrolled from a single center; the selected tSNP could efficiently tag common alleles of TNFSF4 gene and was from GWAS reports; the functional data were checked with external validation using open-access data from other studies, all of which guaranteed reliability. Here, TNFSF4 is linked to lobular neoplasia.