Stem cells from the BPH samples expressing CD49f, CD44, or CD133 markers have been shown to possess monolayer- and spheroid-colony-forming ability, where the highest (98%) recovery of colony-forming cells (CFCs) was achieved by CD49f(+) cells as compared to CD44(+) (17%) or CD133(+) (3%) cells [82]. Here, ITGA6 is linked to benign prostatic hyperplasia.