RPS6KA3 and skin squamous cell carcinoma: The RSK2-induced cell proliferation potential has been proved A431 human skin epidermoid carcinoma cell, SK-ML-5, and SK-MEL-28 MM cells are inhibited by the treatment of kaempferol, a known RSK2 specific natural compound antagonized RSK2 NTKD activity, in the dose dependent manner (17).