The purified residual hematopoietic stem cells were screened for the presence of leukemia-associated mutations and were found to possess some leukemia-associated mutations, such as TET2, NPM1, and SMC1A; however, the FLT3-ITD mutation was not found in these residual hematopoietic stem cells [23]. The gene discussed is FLT3; the disease is leukemia.