In fact, the study of mouse models of leukemia has shown that the fusion oncogene MIZ-TIF2 causes leukemia in mice, but only after a long period of latency; coexpression of FLT3-ITD confers growth factor independency for survival and proliferation, shortens disease latency, and results in an increase in leukemic stem cells [34]. Here, NCOA2 is linked to leukemia.