Table 4 lists the safety profiles measured in our study participants which were not significantly affected by POMx supplementation, except a small but significant increase in aspartate aminotransferase (AST) in healthy controls, and also a small but significant decrease in alanine aminotransferase (ALT) in T2DM patients at 4 weeks versus baseline (P < 0.05). This evidence concerns the gene GPT and type 2 diabetes mellitus.