We have previously reported elevated serum/plasma concentrations of MCT, histamine, IL-6, IL-10 and the soluble TNF receptor I (sTNFRI) in patients presenting to the Emergency Department with anaphylaxis triggered by foods, insect stings or drugs (predominantly antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs)) [25]. This evidence concerns the gene IL6 and anaphylaxis.