Finally, the fact that high levels of murine CXCL13 were also observed in NOD-SCID mice that developed tumors after inoculation of either the R (AIDS-DLBCL) cell line or the BCBL-1 (AIDS-PEL) cell line (Results, not shown) suggests that the 2F7 cell line is not atypical of AIDS-lymphoma cell lines, in terms of being able to promote murine CXCL13 overproduction in tumor-bearing NOD-SCID mice. This evidence concerns the gene CXCL13 and diffuse large B-cell lymphoma.