CXCR4 and gastric cancer: As shown in Table 3, intratumoral CXCR4 expression (HR, 5.07; 95% CI, 2.02 to 12.68; P=0.001) and TNM stage (HR, 15.50; 95% CI, 4.64 to 51.85; P<0.001) were both recognized as independent prognostic factors for overall survival in 97 patients with gastric cancer.