By contrast, NFATC2, STAT1, c-Fos, FosB, FosL1, FosL2, c-Myc, and Bcl-2 were significantly overexpressed in LN-CLL cells compared to PB-CLL and BM-CLL cells (Figure 5A). The gene discussed is FOS; the disease is B-cell chronic lymphocytic leukemia.