We therefore studied the association between the composite VEGF-R2/ERK1/2 score and tumor response (ORR) in patients with an elevated LDH at registration (81 patients), and there was no significant association (P = 0.30 for all patients, P = 0.29 for SCP arm, P = 0.23 for CP arm). The gene discussed is KDR; the disease is neoplasm.