INS and diabetes mellitus: However, diabetes mellitus patients (n = 120) treated with any combination of antidiabetic drugs (metformin, sulfonylurea, insulin, acarbose, thiazolidinediones) had higher median (IQR) excretion (42.1 (58.8) mmol/mol creatinine) than patients (n = 62) on mono-therapy (21.6 (31.0) mmol/mol creatinine) (p = 0.004) or those (n = 60) taking no drugs (14.6 (22.5) mmol/mol creatinine) (p<0.001).