As illustrated in Figure 4A, we found that there were no significant differences between wild-type cells and cells transduced with pLV-GFP and pLL3.7-GFP; this indicated that the tumor growth curve in the cells transduced with pLV-GFP-WT1 was markedly increased compared with control, while the tumor growth curve in cells transduced with pLL3.7-WT1-shRNA was significantly inhibited. This evidence concerns the gene WT1 and neoplasm.