Among the embryos from Tbx20+/-; Tbx3+/- double heterozygous crosses at E8.5, some single or double homozygous embryos showed developmental delay, but over 90% were living (65/71) (Table 2); by E9.25, however, 37% (7/19) were dead (Table 3). Here, TBX20 is linked to Global developmental delay.