IRS1 and neoplasm: Among the upregulated genes, we identified several oncogenes (Ets2, Fyn, Fos, Rab30 and Src), various tumor markers (Cyp1b1, Gpa33, Cd47, Fam129a, st7l, chka, Lgalsbp, Antxr1 and Ly6a) and other genes related to tumor promotion (Cxcl10, Trim25, Grn, Foxc2, Bmp7 and Irs1) (Table 3).