Of the 42 studies investigating the association of the IL-10 gene polymorphisms with SLE, 11 studied the IL10.G microsatellites, 6 studied the IL-10.R microsatellites, 24 studied −1082, 20 studied −819, 26 studied −592, 4 studied −3575 and 4 studied −2763. The gene discussed is IL10; the disease is systemic lupus erythematosus.