Study by Fowler et al [33] has reported that transfection of commercialized miR-124 precursor in GBM cell line A172 resulted in diminished cell migration and invasion as well as downregulated three targeted genes: Ras GTPase activating protein 1 (IQGAP1), cytoskeletal proteins laminin c1 (LAMC1) and integrin β1 (ITGB1). This evidence concerns the gene IQGAP1 and glioblastoma.