CD8A and neoplasm: However, we found a significant increase in the number of tumor-specific CD8+ T cells in HM-1-bearing mice treated with i.p. hyperthermia plus α-GalCer (p<0.0001, combined treatment versus control; p<0.0001, combined treatment versus hyperthermia; p = 0.0026, combined treatment versus α-GalCer alone, Figure 4A).