CRP and Sepsis: Prior studies have associated acute CRP increases (on the order of 10–200 mg/dL) as a marker of sepsis illness severity as well as predicted of sepsis outcomes.[10]–[18] For example, in a series of 50 critically ill sepsis patients, Schmit, et al. observed that CRP on hospital admission was 16.7±10.6 mg/dL and that the magnitude of CPR decrease was associated with response to antimicrobial therapy.