This result was also reflected in our Logical analysis, where we observed that in case of Glioma, Colon and Pancreatic cancer scenarios the number of upstream activator/inhibitor species and downstream activated species of NUC_GLI1 was high compared to the NUC_GLI2 (Figure 4, 5, and 6). Here, GLI2 is linked to familial pancreatic carcinoma.