Since C-X-C motif chemokine 10 (CXCL10, also known as IFN-γ-induced protein 10), a chemokine with chemotactic activity for leukocytes with CXCR3, is thought to be involved in the pathogenesis of glomerular diseases [23], we examined the effect of poly IC and the role of MDA5 in CXCL10 expression in cultured human MCs [13, 14]. Here, CXCL10 is linked to glomerular disorder.