The specific cytokine groups whose differential expression were most closely associated with severe sepsis included the T-cell homeostatic cytokines IL2 and IL7 [6]; cytokines modulating the interaction between innate and adaptive immunity, namely, IL23 and IL27 [7]; and cytokines enhancing bactericidal activity, namely, TNFα and IFNγ [8]. The gene discussed is IL27; the disease is Sepsis.