In vitro, LOX-1 expression is induced by many stimuli related to atherosclerosis, including proinflammatory cytokines such as tumor necrosis factor alpha (TNFα), interleukin-1 (IL-1), and interferon-gamma (IFNγ); angiotensin II; endothelin-1; OxLDL and other modified lipoproteins; free radicals; and fluid shear stress [8–10] (Table 1). This evidence concerns the gene TNF and atherosclerosis.