CASR and familial isolated pituitary adenoma: These genes may include: CDC73, which encodes parafibromin, whose mutations result in the Hyperparathyroid–jaw tumor (HPT–JT) syndrome; the calcium sensing receptor (CaSR), whose mutations result in familial benign hypercalciuric hypercalcemia (FBHH) (Turner et al., 2010); and the aryl hydrocarbon receptor-interacting protein (AIP), a tumor suppressor located on chromosome 11q13 whose mutations are associated with familial isolated pituitary adenomas (FIPA) (Belar et al., 2012).