MEN1 and parathyroid gland adenoma: This would include individuals with: parathyroid adenomas before the age of 30 years or multigland parathyroid disease; gastrinoma or multiple pancreatic islet cell tumors at any age; or individuals who have two or more MEN1-associated tumors, which are not part of the classical triad of parathyroid, pancreatic islet and anterior pituitary tumors (e.g. parathyroid tumor plus adrenal tumor) (Thakker et al., 2012).