For example, a detailed study of five unrelated families with the same 4-bp deletion in codons 210 and 211 (Table 3) revealed a wide range of MEN1-associated tumors (Bassett et al., 1998; Lemos and Thakker, 2008; Thakker, 1998); all affected family members had parathyroid tumors, but members of families 1, 3, 4, and 5 had gastrinomas, whereas members of family 2 had insulinomas. Here, MEN1 is linked to pancreatic insulinoma.