CRLF2 and acute lymphoblastic leukemia: The contradictory results reported by Cario et al. [24], in which CRLF2 overexpression was associated with poor EFS in the ALL-BFM 2000 protocol (6-year EFS 28% vs. 71%, P = 0.001), were thought to be mainly due to the effect of the P2RY8-CRLF2 fusion, and not simply CRLF2 overexpression.