IL10 and myocardial infarction: In the experimental model of acute MI, the adoptive transfer of CD4+CD25+ regulatory T cells improved left ventricular contraction and cardiac function, which may be mediated by the local reduction of IFN-γ levels [97], and by the decrease in the recruitment of neutrophils, macrophages and lymphocytes as well as by the down-regulation of TNF-α and IL-1β expression and elevation of IL-10 at the site of injury [98].