When sequenced for 9 Usher Syndrome genes, and screened for USH2A deletions, duplications and for the pathogenic variant USH2A: c.7595-2144A>G, 77% (93/121) of USH2 families have two pathogenic/UV4/UV3 mutations, 11% (13/121) have one pathogenic/UV4/UV3 mutation and 12% (15/121) have no pathogenic/UV4/UV3 variants. This evidence concerns the gene USH2A and Usher syndrome.