At 3 weeks, the main regulated pathways were chemokine signaling, glycogen degradation II, cAMP-mediated signaling, glycogen degradation III, role of IL-17A in arthritis, agranulocyte adhesion and diapedesis, IL-22 signaling, agrin interactions at neuromuscular junction, IL-17A signaling in gastric cells, and role of JAK family kinases in IL-6-type cytokine signaling. This evidence concerns the gene AGRN and arthritic joint disease.