IL-6, which is produced mainly by mononuclear cells, macrophages and a smaller percentage of fibroblasts, endothelial cells, T and B lymphocytes, chondrocytes and amnion cells [43], is a pleiotropic cytokine that causes carcinogenesis, promotes tumor growth and facilitates tumor cell metastasis [25]–[27]. The gene discussed is IL6; the disease is neoplasm.