CDH2 and familial pancreatic carcinoma: EMT, a developmental program in which epithelial cells acquire a spindle cell morphology and exhibit cellular motility, has been proposed as a prerequisite for the invasion and dissemination of carcinoma cells and as a precedent to pancreatic cancer formation and metastasis [6], Therefore, we measured the expression of the major epithelial marker E-cadherin and the mesenchymal markers vimentin, N-cadherin and Slug in the tumor tissues of the two groups.