Despite the fact that HSV-2 infection in Fas or FasL-deficient mice leads to the increased infiltration of neutrophils to the site of infection [2] we observed decreased infiltration of monocytes at 3 day of infection in comparison to wild-type mice; on the other hand, at 7 day post-infection, an increased percentage of monocytes could be detected within the HSV-2 infected sites in Fas- and FasL-deficient mice in contrast to wild-type mice where lesser infiltration of monocytes was detected. The gene discussed is FAS; the disease is infection.