Meta-analysis of rs11594656 of IL2RA gene among 17,523 T1D cases and 19,909 controls [22], [30], [31], [37] indicated that rs11594656 of IL2RA gene was significantly associated with T1D risk in the Caucasian and Japanese populations (Figure 2, the overall OR = 0.86, 95% CI = 0.82–0.91, P<0.00001). This evidence concerns the gene IL2RA and type 1 diabetes mellitus.