CFH and age-related macular degeneration: Association of the Y402H (rs1061170) variant of CFH with AMD has been described in several populations worldwide [6], [20], with TC and CC genotype being approximately 2.5 and 6 times extra likely to have AMD than patients having TT genotype [21], and this was later confirmed in Italian [22], French [7], British [6], Russian [14] and Icelandic [20] populations.