Even the monoclonal antibody HECA-452 which has a broader specificity (CA19-9 and CD15s among other carbohydrate moieties) had no inhibitory effect on E- and P-selectin binding to the CEL and CML cells, but blocked E-selectin binding to PaCa 5061 cells (not shown). Here, SELE is linked to chronic myelogenous leukemia, BCR-ABL1 positive.