[33]–[38] In this study we could also show, with a highly sensitive PCR method and highly sensitive measurements of CRP, that parasite load associates with CRP levels also in asymptomatic individuals. It appears that it is not the occurrence of P. falciparum infection per se that leads to elevated CRP levels but the intensity of the infection. CRP has also been proposed to be implicated in the susceptibility to malaria and to provide an explanation to ethnic differences in P. falciparum susceptibility [39]. The gene discussed is CRP; the disease is infection.