BRD2 and Azoospermia: [7] Men with non-obstructive azoospermia (NOA) may have severely deficient spermatogenesis and inadequate sperm production. [8] Non-obstructive azoospermia is most frequently characterized by an elevated FSH and small volume testes, and treatment historically involved donor inseminations or adoption. Sperm production is not uniform throughout the testes in men with NOA which leads to difficulty in surgically isolating sperm. However, if sperm are recovered, subsequent IVF-ICSI treatment can produce viable offspring for these patients. [8].