To validate our microarray findings, we conducted quantitative RT-PCR analysis for FJX1 mRNA and found FJX1 mRNA expression levels were between five- and seventy-fold higher in colon cancer tissues than in normal adjacent tissue from the same patient (Figure 1B, one-sided t-test P<0.0004). The gene discussed is FJX1; the disease is malignant colon neoplasm.