In silico analysis of FJX1 mRNA expression in clinically annotated samples collected at Vanderbilt Medical Center (VUMC) and the H. Lee Moffitt Cancer Center (MCC) (see Table S2 for clinical information) revealed that FJX1 mRNA is significantly increased across all stages of CRC as compared to normal colorectal tissue and colorectal adenomas (Figure 1A, stage 1, P<0.02; stages 2, 3 and 4, P<0.00001). The gene discussed is FJX1; the disease is colorectal adenoma.