CYP1B1 and open-angle glaucoma: Twelve previously reported CYP1B1 mutations [25-35] and a novel variant (c.1403_1429dup, p.Arg468_Ser476dup; Table 4 and Table 5) were initially detected in nine index patients with PCG, three with POAG, two with JOAG and two with ARS (Table 4 and Table 5).