The two coding exons of CYP1B1 were analyzed with PCR and sequencing in 45 index patients with POAG, 25 index patients with PCG, 21 index patients with JOAG, four index patients with Axenfeld-Rieger syndrome (ARS), and seven index patients with other types of glaucoma (Table 2). This evidence concerns the gene CYP1B1 and open-angle glaucoma.