In addition, it has been shown that WIF1 functions as a tumor suppressor in melanoma, nasopharyngeal, esophageal, stomach, brest, and lung cancers (Clément et al. 2008; Chan et al. 2007; Taniguchi et al. 2005; Lin et al. 2007, 2008; Kim et al. 2007; Wissmann et al. 2003), and overexpression of WIF1 inhibites the growth of cells from lung and bladder cancers (Tang et al. 2009). This evidence concerns the gene WIF1 and lung cancer.