WIF1 and urinary bladder carcinoma: The downregulation of WIF1 by promoter hypermethylation has been reported in various human malignancies including carcinoma of urinary bladder, lung, brest, esophagus and stomach (Ding et al. 2009; Urakami et al. 2006; Mazieres et al. 2004; Ai et al. 2006; Clément et al. 2008; Chan et al. 2007; Taniguchi et al. 2005).