LRRK2 and astrocytoma (excluding glioblastoma): Astrocytes were selected as a cell type to carry out these experiments based upon previous data highlighting LRRK2 expression in these cells [30], and to march as closely as possible to the H4 cells used as the main cell model in this study (H4 cells are classified as a neuroglioma line, but are likely to have been derived from an astrocytoma [40,41]).