INS and type 2 diabetes mellitus: The primary objective of the present retrospective study (LANTus utilisation in real life versus PREmix Insulin, PRELANTI) was to assess the efficacy of intensification of treatment, by measuring the change in HbA1c, of two main insulin treatment schemes: (a) glargine once daily in the evening and (b) biphasic human insulin twice daily (bd) in patients with T2DM on concomitant therapy with oral antidiabetic drugs (OAD).