Levels of Ang-2, an endothelial barrier-destabilizing factor, were higher in patients that developed septic shock (6,494.0 pg/ml, range 1,730.0 to 49,611.0 pg/ml) compared to patients with non-complicated sepsis (4,467.0 pg/ml, range 1,289.0 to 37,318.0 pg/ml; Mann-Whitney test: P = 0.02) (Figure 2). Here, ANGPT2 is linked to Sepsis.