Both of these categories were linked to changes in adiponectin, creatine kinase-MB, C-reactive protein, haptoglobin, matrix metalloproteinase 7 and transferrin, although interferon inducible T cell α-chemoattractant (ITAC) was associated specifically with hematological disease and thyroglobulin was specifically related to endocrine system disorders. This evidence concerns the gene HP and hematologic disorder.