To further understand the role of adiponectin in the pathogenesis of CHB patients with steatosis, we conducted a study which examined the hepatic expression of adiponectin, and its receptors in patients with CHB, and then compared patients with or without steatosis to determine whether there was any correlation between the histopathological progression of CHB, and the expression of adiponectin, and its receptors. The gene discussed is ADIPOQ; the disease is steatosis.