Molecular mechanistic research showed that Matrine regulated tumor regulators, including NF-κB, XIAP, Bcl-2 and Bax, etc., as well as interacted with cell signal pathways, including extracellular signal-regulated kinases (ERK) and Fas/FasL, etc. [22,28–34]. The gene discussed is NFKB1; the disease is neoplasm.