Moreover, COMT genotype has been found to be an important predictor of planning performance and its concomitant BOLD signal in fronto-parietal areas in patients with Parkinson′s disease (PD: (Foltynie et al., 2004; Hoogland et al., 2010; Williams-Gray et al., 2009; Williams-Gray, Hampshire, Barker, & Owen, 2008; Williams-Gray, Hampshire, Robbins, Owen, & Barker, 2007). The gene discussed is COMT; the disease is Parkinson disease.