As predicted, a two-component curve represented the rate of reduction of methemoglobin in a sample that consisted of an artificial mixture of erythrocytes from a G6PD-deficient male with those from a normal subject as well as in a sample from a female heterozygous for G6PD deficiency (Figure 6). Here, G6PD is linked to hyperinsulinemic hypoglycemia, familial, 4.