GAP43 and amyotrophic lateral sclerosis: Therefore, the multifunctional properties of M30 suggest that it mayoffer extraordinary potential as a drug for the treatment of PD, especially PDdementia46 and AD.47,48 More recently in a transgenic G93A superoxidedismutase (SOD) model of amyotrophic lateral sclerosis (ALS) this extends thelife-span of these animals and has neurogenic activity in NCS-34 rat motor neuronsby inducing neurite formation with increased neuronal GAP-43.45