Other notable proteins found to be specific to the Zn-treated embryos included a factor regulating the length of the apical tuft, AnkAT-1 [Yaguchi et al., 2010] (SPU_024961), a protein defective in a patient with Usher syndrome, Usherin [Weston et al., 2000], a syndecan-binding protein syntenin (SPU_009549) and fibrocystin (SPU_023486). The gene discussed is PKHD1; the disease is Usher syndrome.