TNF and neoplasm: Indeed, TNF-α is produced by a wide variety of tumour cells, including those of B cell lymphoma [87], cutaneous T cell lymphoma [88], megakaryoblastic leukaemia [89], adult T cell leukaemia [90], AML [91], CLL [92],ALL [93], breast carcinoma [94], colon carcinoma, lung carcinoma, squamous cell carcinoma, pancreatic cancer [95], ovarian carcinoma [96].